Epifanio Comis was a student of Agatella Catania, Boris Petrushansky and Pietro Rattalino.
He has toured as a soloist throughout Europe, Asia, Russia, and the United States. He has performed with numerous world class orchestras including the George Enescu Philharmonic Orchestra of Bucharest, the Radio Orchestra of Bucharest, the Philharmonic Orchestra of Kiev, the Karlovy Vary Symfonic Orchestra, the Philharmonic Orchestra of Szeged, the Philharmonic Orchestra of Cluj, the Tulare County Symphony Orchestra of California, the Plainfield Symphony Orchestra, the Orquestra Sinfonica UANL of Mexico, the Orchestra Sinfonica del Teatro Bellini di Catania, the Orchestra Sinfonica Siciliana, the Orchestra Filarmonica del Teatro Bellini, the Osaka Symphoniker, the Kioto Symphony. His recitals in the USA and Asia have brought him great critical acclaim.
Epifanio Comis gives masterclasses in important Academies and Universities like Manhattan School of Music, Chopin Academy Warsaw, Royal Conservatoire Mons, Ecole Normale in Paris, Ciaikovsky Conservatory Moscow, Bucarest Music Academy.
He is also a very acclaimed teacher. His students achieved top prizes in the most important world piano competitions.
In 2013 he was awarded at the Moscow Conservatory with the Sergei Rachmaninov International Award together with Vladimir Ashkenazy, Valery Gergiev, Francesco Nicolosi and Nicolai Lugansky.
He is currently Director and Professor at the Conservatory of Music “Vincenzo Bellini” in Catania.